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  • ?2017-09-13
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1.???JMJD1C???? 2. ???????

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·Zhu N, Chen M, Eng R, Sinha AU, Rahnamay NF, Koche R, Al-Shahrour F, Minehart JC, Chen CW, Deshpande AJ, Xu H, S. Chu H, Ebert BL, Roeder RG,  Armstrong SA. Jmjd1c is required for MLL-AF9 and HOXA9 Mediated AML Stem Cell Self-Renewal. J. Clin. Invest. 2016 Mar 1;126(3):997-1011.

·Chen M, Zhu N, Liu X, Laurent B, Tang Z, Eng R, Shi Y, Armstrong SA, Roeder RG. JMJD1C is required for the survival of acute myeloid leukemia by functioning as a coactivator for key transcription factors. Genes Dev. 2015 Oct  15;29(20):2123-39.

·Chen M, David CJ, Manley JL (2012). Concentration-dependent control of pyruvate kinase M mutually exclusive splicing by hnRNP proteins. Nat Struct Mol Biol. 19(3):346-54.

·7.David CJ#, Chen M#, Assanah M, Canoll P, Manley JL (2010) HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer. Nature 463: 364-8. #, These authors contributed equally to this work.

·8.Chen M, Manley JL (2009).  Mechanisms of alternative splicing regulation: insights from molecular and genomics approaches. Nat Rev Mol Cell Biol. 10(11):741-54.

 

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